Endometriosis-associated Lyme.

J Obstet Gynaecol. 2010 Feb;30(2):184-6.

Endometriosis-associated Lyme.

Matalliotakis IM, Cakmak H, Ziogos MD, Kalogeraki A, Kappou D,
Arici A.

Department of Obstetrics and Gynecology, University of Crete,
Heraklion, Crete, Greece.

The aim of this study is to report three cases of patients with
endometriosis and infertility, and associated with Lyme disease.
The medical files of 405 women with endometriosis and 200 without
endometriosis were studied retrospectively. We report 3 cases
with endometriosis and Lyme disease. Of 405 patients with
endometriosis treated in our study over a 6-year period, 3(0.8%)
had Lyme disease. All cases presented with typical erythema
migraines, fever and fatigue. The serological findings were
positive for Borrelia burgdorferi, for 3 cases. Two out of 3
women underwent IVF-ET procedures and one of them conceived in
the first cycle without complication during pregnancy or after
childbirth recorded. We concluded that women with endometriosis
are more likely to have chronic fatigue syndrome, systemic lupus
erythematous, Sjogren's syndrome, rheumatoid arthritis, multiple
sclerosis, and other autoimmune inflammatory and endocrine
diseases. A review of the literature confirms the uniqueness of
the co-existence of Lyme disease in women with endometriosis in
these cases.

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