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#1249 - 02/10/07 07:24 PM
Papillitis, Lyme disease, and cats.
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Angls4hope
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Registered: 11/29/06
Posts: 2069
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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed
Eye. 2007 Jan 19; [Epub ahead of print]
Papillitis, Lyme disease, and cats.
* Mishra SK, * Murjaneh S, * Morgan MS, * Simcock PR, * Glover S.
Correspondence: PR Simcock, West of England Eye Unit, Royal Devon and Exeter Hospital (Wonford), Barrack Road, Exeter EX2 5DW, UK Tel: + 44 139 240 6008; Fax: + 44 139 240 6022. E-mail: psimcock@hotmail.com
Sir Papillitis, Lyme disease and cats
We present a case of papillitis caused by Lyme disease in the UK. We also highlight the increased risk of Lyme disease in cat owners.
Case report
A 50-yr-old man presented with a 10 day history of central blurring of vision in his left eye. He had noted a rash on his right forearm 6 months previously. There was no definite history of a tick bite or of visiting high-risk areas, but his cat had ticks. Unaided vision was 6/6-3 right and 6/4 left improving to 6/12 with pin hole. There was a mild left relative afferent pupillary defect, a paracentral scotoma inferior fixation, and mild impairment of colour vision, and a pink swollen optic disc on this side.
Lyme disease antibody titres were +ve for ELISA and Western blot methods, confirmed by a reference lab. The following investigations were normal or negative: FBC, ESR, Auto-antibody screen, coagulation screen, angiotensin converting enzyme anticoagulant. The patient was treated with a 2 week course of IV ceftriaxone. The visual acuity however did not change with treatment.
Comment
Lyme disease can mimic many ophthalmic conditions. It has been reported to cause eyelid oedema, conjunctivitis, keratitis, episcleritis, anterior uveitis, vitritis, choroiditis, endophthalmitis, neuroretinitis, exudative retinal detachment, retinal vasculitis, optic neuritis, optic atrophy, pseudomotor cerebri, paresis of cranial nerves and orbital myositis. Optic neuritis in Lyme disease may or may not respond to treatment with antibiotics.
In the mid-1970s, Dr Allen Steere and colleagues noted that a significant number of patients with Lyme disease had cats and had noted ticks on their pets, compared with their unaffected neighbours. Lyme disease is now known to occur in cats, and Borrelia burgdorferi has been isolated from the tissue of adult and nymphal ticks removed from domestic cats. The increased risk of Lyme disease in cat owners is not widely known. This case report may represent Lyme disease causing papillitis transmitted from the patient's cat.
References
Sorry I'm not copy typing out the references too! but if anyone would like the entire article in pdf just email me back.
best wishes
Gill
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